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KMID : 0388220140210010036
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Journal of the Korean Rheumatism Association
2014 Volume.21 No. 1 p.36 ~ p.39
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Treatment with Rituximab in a Patient with Refractory Felty Syndrome and Low Rheumatoid Arthritis Disease Activity: A Case Report
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Chang Sung-Hae
Yang Ji-Ae
Lee Sang-Jin
Park Jun-Won
Shin Ki-Chul
Lee Eun-Bong
Song Yeong-Wook
Lee Eun-Young
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Abstract
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Felty syndrome (FS) is a rare manifestation in rheumatoid arthritis (RA) characterized by neutropenia and spleno-megaly. Treatment for FS is not well established because there has been no randomized controlled study. A few re-cent reports found rituximab effective in patients with re-fractory FS. According to those reports, most patients with RA and FS had active arthritis. Here we report a case of a patient with glucocorticoid dependent and disease-modify-ing anti-rheumatic drugs (DMARDs) refractory FS and qui-escent RA who was successfully treated with rituximab.
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KEYWORD
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Felty syndrome, Rituximab, Rheumatoid ar-thritis
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